Carboxymethylcellulose Calcium Manufacturer & Supplier | Pharmaceutical Excipient CAS 9050-04-8
- Wonsen
- China
- 30 days
- Always Available
Carboxymethylcellulose Calcium (Carmellose Calcium, CAS 9050-04-8) is a high-quality pharmaceutical excipient widely used as a tablet disintegrant, binder, and formulation aid. We supply high purity Carboxymethylcellulose Calcium powder with reliable quality and stable supply for global pharmaceutical manufacturers.
Carboxymethylcellulose Calcium
(CDE REGISTRATION NO.: F2023000328)
Name: Carboxymethylcellulose Calcium
Other Name: Carmellose Calcium
CAS No.: 9050-04-8
Packaging: 1kg/bag/carton; 5kg/bag/carton; 20kg/bag/drum
Appearance:
White or yellowish white powder; hygroscopic after drying.
Practically insoluble in acetone, in ethanol (96 per cent) and in toluene. It swells with water to form a suspension.
Quality Standard: CP2020/USP2024/EP11.0/JP18
Specifications:
| Alpha code | Refer to GOTOKU code | Specifications |
| AG5401 | / | / |
| AG5402 | ECG-505 | D90: 200 mesh |
Features:
Carboxymethylcellulose Calcium is primarily used in tablets as a binder, diluent, and disintegrant. Although it is insoluble in water, it is an effective tablet disintegrant because it expands several times its original volume upon contact with water.
Applications:
| Dosage form | Application | Dosage |
| Oral solid preparations | Disintegrant | 1-5% |
| Oral solid preparations | Binder | 0.5-2% |
| Liquid preparations | Thickening Agent, Suspending Agent | 1%-5% |
| Topical Formulations | Thickening Agent, Suspending Agent | 1%-5% |
| Wound Dressings | Absorbent, Hemostatic Agent | 5%-15% |
Advantages:
■Carboxymethylcellulose Calcium is the only calcium-based disintegrant available worldwide.
■Carboxymethylcellulose Calcium can rapidly absorb water, swell, and disintegrate within a short time.
■Carboxymethylcellulose Calcium is suitable for both wet granulation and direct tableting processes.
■It is derived from natural materials, exhibiting good biocompatibility, non-toxicity, excellent disintegration properties, and biodegradability.
■High Stability: Stable against heat, light, air, and microbial degradation.
Incompatibilities:
■CMC-Ca may react with certain drug components under acidic conditions (e.g., with chlorides or sulfates).
■High concentrations may affect tablet hardness.
Storage:
Preserve in tight containers.
